Advancing Circular Economy Technologies
for Supply Chain Resilience

Connecting Kentucky and Tennessee into a national hub for circular economy innovation through supply chain resilience, talent development and industry collaboration.


GAME Change is building America’s first regional innovation hub for circular manufacturing and supply chain resilience.


Rooted in Kentucky and Tennessee, we are transforming the way manufacturing and supply chains work by turning materials waste into economic opportunity, creating quality jobs and advancing regional resilience.

More than 60 partners from research, industry, government and communities are aligned around a single mission:
Build the Southeast Commerce Corridor (SCC) into a global leader in circular innovation by 2035.

Our work is focused on enabling materials recovery, digital supply chain connectivity and the infrastructure needed to scale circular technologies and talent.

THIS IS NOT A PROJECT. IT'S A MOVEMENT.

And this region is ready.

Our R&D Focus Areas:

At GAME Change, we are building a national circular economy innovation engine with a clear focus on enabling technologies and priority sectors. Our efforts are concentrated in two critical domains:

Sector Focus

We apply these innovations in high-impact sectors where circular strategies can create the most value, including transportation (automotive, aerospace, logistics and related components) and infrastructure, including construction materials and systems that support roads, power grids, telecommunications and data centers.

Technical Focus

Our work centers on innovations that support circularity across the full product lifecycle by designing materials, products and processes for upcycling, reuse and recovery. These efforts are paired with digital technologies such as artificial intelligence, digital twins and automation to improve efficiency, traceability and connectivity.

Built to Grow. Ready to Adapt.

1.12 Billion

Pounds of production waste created by manufacturing in KY/TN annually

45% Materials & 55% Energy

Total current global emissions related to materials or energy

Source: Ellen MacArthur Foundation

45% Circular Economy & 55% Emerging Tech

Most effective strategies for reducing global emissions by 2025

Kentucky and Tennessee have experienced record manufacturing growth, driven by a 40.4% increase in manufacturing outputs from 2010 to 2020. As the region grows, it must navigate several key challenges:

Fragile Supply Chains

Limited resilience in domestic production and distribution networks

Industrial Waste Management

Few scalable options for handling and repurposing materials

Material Independence

Region lags in industry R&D

Technology Scaling Infrastructure

Lack of infrastructure for commercializing circular manufacturing technologies

Workforce Shortages

Gaps in skilled labor across the manufacturing sector

Strategic innovation, regional collaboration and sustainable investment are essential to tackling these challenges and securing long-term success.

Our Strategic Approach: GAME Change for the Southeast Commerce Corridor (SCC)

To address the pressing challenges facing Kentucky and Tennessee, ranging from materials waste and supply chain gaps to workforce shortages and lack of circular technology scaling infrastructure, we’ve launched a bold, region-wide strategy: GAME Change.

This strategy is built around three pillars:

Clear Priorities

Focusing on workforce development, supply chain resilience and circular economy innovations.

Measurable Outcomes

Driving real results, including reductions in manufacturing waste, new startups and expanded R&D investment.

Targeted Programs

Delivering impact through new centers, digital platforms, venture studios and collaborative ventures.

GAME Change's Strategy for the SCC including priorities, programs and outcomes

Game Change Leadership Team

Project Director

Ian McClure, J.D., LL.M., University of Kentucky

Talent & Workforce Development

Dr. Kris Williams, KCTCS

Innovation Leadership

Monique Kuykendoll Quarterman, Kentucky Cabinet for Economic Development

Use-Inspired Research & Development

Dr. Doug Adams, Vanderbilt University

IDEA Engine

Kayla Meisner, Kentucky Commercialization Ventures

Ecosystem of Partners & Industry

Marc Gibson, University of Tennessee at Knoxville

Innovation Translation to Practice

Robert Turner, Tennessee State University

Scale Centers & Vendor Studios

Will Metcalf, University of Louisville

Evaluation & Assessment

Dr. Shannon Sampson, University of Kentucky

Speed to Market

Vijay Kamenini, Metals Innovation Initiative

Core Partners

KENTUCKY

TENNESSEE

Research reported on this website was supported by the National Science Foundation under Award #2302947. The opinions, findings, and conclusions or recommendations expressed are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.